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KMID : 0191119920070020079
Journal of Korean Medical Science
1992 Volume.7 No. 2 p.79 ~ p.84
POEMS syndrome--a case report
Kim JW
Lee SK/Ha KM/Kim KH/Joh GY/Kim HJ/Yang SO/Hong SH
Abstract
POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
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